What are the genotype and phenotype of individual 1, 2, and 3 based on the given data?
The genotype of Individual 1 is 'aa' which means they are homozygous recessive. This would result in the phenotype of sickle-cell anemia. Individual 2 and 3 would be a carrier and normal respectively due to their dominant alleles.
Understanding Genotype and Phenotype
Genotype: The genotype refers to the genetic makeup of an individual, specifically the combination of alleles they possess. In this case, the alleles are represented by letters: 'A' for a normal allele and 'a' for a sickle cell allele.
Individual 1:
The genotype of Individual 1 is 'aa', indicating that they have two copies of the sickle cell allele. This makes them homozygous recessive for sickle cell. As a result, Individual 1's phenotype would be sickle-cell anemia.
Individual 2 and 3:
Individual 2 has the genotype 'Aa', making them a carrier for the sickle cell allele. Their phenotype would be normal since the dominant normal allele masks the effects of the sickle cell allele. Individual 3, with the genotype 'AA', has two copies of the normal allele, resulting in a normal phenotype.
It is important to understand how genotypes determine the phenotypes of individuals in genetic inheritance. By analyzing the genotypes provided, we can accurately predict the phenotypes based on the genetic information present in the alleles.